Last Friends tackles issues that afflict the current generation. Michiru's mother has brought a man back to their home and she is bullied at her workplace where she works as a beauty parlour assistant. She starts cohabiting with her boyfriend, a good young man who works at the Child Welfare Division and the only person who can give her emotional , but ends up the victim of domestic violence and becomes fearful of love. The boyishly charming Ruka was a classmate of Michiru's in junior high school. She has performed brilliantly as a motocross racer and aims to win the national championship, but as the story progresses, a deep worry that she can neither confide in her parents or close friends grows evident. Takeru is a hair and makeup artist acquainted with Ruka. He is a good confidant to females due to his kindness and perceptiveness, and finds himself attracted to Ruka but has a phobia of sex as a result of a past trauma. The three of them become house mates and through their associations with others, gain the capacity to be positive about life.